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1 作者 Ruilope L.M., Dukat A., Bohm M., Lacourciere Y., Gong J., Lefkowitz M.P.
题目 Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: A randomised, double-blind, placebo-controlled, active comparator study.
期刊  Lancet. 2010;375:1255–1266. doi: 10.1016/S0140-6736(09)61966-8.

2 作者 Kario K., Sun N., Chiang F.T., Supasyndh O., Baek S.H., Inubushi-Molessa A., Zhang Y., Gotou H., Lefkowitz M., Zhang J.
题目 Efficacy and safety of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor, in Asian patients with hypertension: A randomized, double-blind, placebo-controlled study.
期刊  Hypertension. 2014;63:698–705doi: 10.1161/HYPERTENSIONAHA.113.02002.

3 作者Wang J.G., Yukisada K., Sibulo A., Jr., Hafeez K., Jia Y., Zhang J.
题目 Efficacy and safety of sacubitril/valsartan (LCZ696) add-on to amlodipine in Asian patients with systolic hypertension uncontrolled with amlodipine monotherapy.
期刊   J. Hypertens. 2017;35:877–885. doi: 10.1097/HJH.0000000000001219.

4作者Joseph L., Izzo J., Zappe D.H., Jia Y., Hafeez K., Zhang J.
题目Efficacy and Safety of Crystalline Valsartan/Sacubitril (LCZ696) Compared With Placebo and Combinations of Free Valsartan and Sacubitril in Patients With Systolic Hypertension: The RATIO Study.
期刊  J. Cardiovasc. Pharmacol. 2017;69:374–381.

5 作者Schmieder R.E., Wagner F., Mayr M., Delles C., Ott C., Keicher C., Hrabak-Paar M., Heye T., Aichner S., Khder Y., et al.
题目 The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: The results of a randomized, double-blind, active-controlled study.
期刊 Eur. Heart J. 2017;38:3308–3317. doi: 10.1093/eurheartj/ehx525

6作者Wang T.D., Tan R.S., Lee H.Y., Ihm S.H., Rhee M.Y., Tomlinson B., Pal P., Yang F., Hirschhorn E., Prescott M.F., et al.
题目 Effects of Sacubitril/Valsartan (LCZ696) on Natriuresis, Diuresis, Blood Pressures, and NT-proBNP in Salt-Sensitive Hypertension.
期刊  Hypertension. 2017;69:32–41. doi: 10.1161/HYPERTENSIONAHA.116.08484.

7作者Williams B., Cockcroft J.R., Kario K., Zappe D.H., Brunel P.C., Wang Q., Guo W.
题目Effects of Sacubitril/Valsartan Versus Olmesartan on Central Hemodynamics in the Elderly With Systolic Hypertension: The PARAMETER Study.
期刊  Hypertension. 2017;69:411–420. doi: 10.1161/HYPERTENSIONAHA.116.08556.

8作者Huo Y., Li W., Webb R., Zhao L., Wang Q., Guo W.
题目 Efficacy and safety of sacubitril/valsartan compared with olmesartan in Asian patients with essential hypertension: A randomized, double-blind, 8-week study.
期刊 J. Clin. Hypertens. 2019;21:67–76. doi: 10.1111/jch.13437.

第2篇

第8篇课可免费在线阅读。链接:https://onlinelibrary.wiley.com/doi/epdf/10.1111/jch.13437

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