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临床药师网(linyao.net)免责声明
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1、重点警示;2、用药目的;3、用药禁忌;4、使用前注意事项;5、药物相互作用;6、怎样使用该药;7、重要的用药安全信息;8、该药可能的副作用;9、副作用发生时的处理;10、过量使用的处理;11、如何贮存该药;12、补充信息。
以奥沙利铂为例:
Read this medicine information sheet carefully each time you get this medicine filled.This medicine information sheet has been written specifically for female patients.This medicine information sheet has been written specifically for male patients.
Warning Use this medicine only under close medical supervision. This medicine may rarely cause severe and sometimes fatal allergic reactions during administration. Notify your doctor immediately if you experience signs of an allergic reaction such as rash, hives, itching, dizziness, swelling, excessive sweating, chest pain, disorientation, shortness of breath, trouble breathing, or fainting.
This medicine is used for:
Treating advanced cancer of the colon or rectum in certain patients. It is usually used in combination with other medicines.
This medicine is an antineoplastic. It works by killing cancer cells and slowing tumor growth.
Do NOT use this medicine if:
you are allergic to any ingredient in this medicine or to another platinum product (eg, cisplatin, carboplatin)
you have certain lung problems (eg, pulmonary fibrosis, interstitial lung disease) or bone marrow disease
Contact your doctor or health care provider right away if any of these apply to you.
Before using this medicine:
Some medical conditions may interact with this medicine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have kidney or liver problems, blood disorders (eg, anemia), or nerve disorders
Some MEDICINES MAY INTERACT with this medicine. Tell your health care provider if you are taking any other medicines, especially any of the following:
Anticoagulants (eg, warfarin) because the risk of bleeding may be increased
Medicines that may harm the kidney (eg, aminoglycoside antibiotics [eg, gentamicin], amphotericin B, cyclosporine, nonsteroidal anti-inflammatory drugs [NSAIDs] [eg, ibuprofen], tacrolimus, vancomycin) because the risk of this medicine's side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the kidney
This may not be a complete list of all interactions that may occur. Ask your health care provider if this medicine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use this medicine:
Use this medicine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with this medicine. Talk to your pharmacist if you have questions about this information.
This medicine is usually administered as an injection at your doctor's office, hospital, or clinic.
Do not use this medicine if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
If nausea, vomiting, or loss of appetite occurs, ask your doctor or pharmacist for ways to lessen these effects. Also, other medicines may be given before and after therapy with this medicine to help reduce these effects.
It is important to take each dose as scheduled. If you must miss a dose, contact your doctor right away.
Ask your health care provider any questions you may have about how to use this medicine.
Important safety information about this medicine:
This medicine may cause dizziness, fatigue, balance problems, temporary vision loss, or other vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use this medicine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.
This medicine may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
This medicine may lower the ability of your body to fight infection. Avoid contact with people who have colds or other infections. Do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first.
Do not receive a live vaccine (eg, measles, mumps) while you are taking this medicine. Talk with your doctor before you receive any vaccine.
Some patients using this medicine have developed severe and sometimes fatal lung problems. Tell your doctor right away if you develop dry cough, shortness of breath, or chest pain.
This medicine may cause burning, numbness, or tingling in the hands or feet, or around the mouth or throat. It may also cause jaw spasms, odd feelings in your tongue, joint or eye pain, or chest pressure. Exposure to cold temperatures or cold objects may make these symptoms worse. Avoid drinking cold drinks and ice while receiving this medicine. Cover exposed skin before exposing yourself to cold temperatures or cold objects. Tell your doctor if these persist or become bothersome.
You can reduce sensitivity to cold temperatures or objects by doing the following: cover yourself with a blanket while receiving medicine; do not breathe deeply when exposed to cold air; wear warm clothing in cold weather at all times; cover your mouth and nose with a scarf or a ski cap to warm the air that goes into your lungs; wear gloves when removing items from the freezer and refrigerator or when touching car doors, mailboxes, or other metal objects; drink lukewarm fluids; drink beverages with a straw; do not use ice chips if you have nausea or mouth sores; do not put ice packs on your body; do not run the air conditioning at high levels in the house or car during hot weather; if you get cold, warm up only the cold part of your body; warm cold hands up with warm water.
Diabetes patients - This medicine may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Women who may become pregnant should use an effective form of birth control while they are using this medicine. Talk with your doctor if you have questions about effective birth control.
Lab tests, including complete blood cell counts and liver function, may be performed while you use this medicine. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use this medicine with caution in the ELDERLY; they may be more sensitive to its effects, especially diarrhea, dehydration, low potassium levels, fatigue, and fainting.
This medicine should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: This medicine has been shown to cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using this medicine while you are pregnant. It is unknown if this medicine is excreted in breast milk. Do not breast-feed while taking this medicine.
Possible side effects of this medicine:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; decreased appetite; diarrhea; dizziness; fatigue; gas; hair loss; headache; heartburn; hiccups; increased tears; muscle or joint aches; nausea; pain, redness, or swelling at the injection site; runny nose; taste changes; trouble sleeping; vomiting; weight loss.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; calf or groin pain, swelling, or redness; change in the amount of urine produced; chest pain or pressure; confusion, slurred speech, or one-sided weakness; coughing up blood; disorientation; excessive sweating; fainting; flushing; mouth sores or swelling; nosebleeds; red, swollen, blistered, or peeling skin; severe or persistent diarrhea or vomiting; severe or persistent dizziness; severe or persistent pain, swelling, or redness at the injection site; severe or persistent tiredness or weakness; shortness of breath; sudden, severe headache; swelling of the hands, ankles, or feet; symptoms of dehydration (eg, very dry eyes, mouth, or skin; unusual thirst); symptoms of infection (eg, fever, chills, or sore throat; painful urination; productive cough); symptoms of liver problems (eg, yellowing of the skin or eyes; dark urine; pale stools; persistent nausea, stomach pain, or loss of appetite); symptoms of low potassium levels (eg, irregular heartbeat, muscle pain or cramps); symptoms of stomach or bowel bleeding (eg, black, tarry stools; vomit that looks like coffee grounds); trouble walking, swallowing, speaking, or performing other daily tasks (eg, writing, buttoning); unusual bruising or bleeding; vision loss or other vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include chest pain; diarrhea; easy bruising or bleeding; fatigue; muscle spasms in the face; persistent change in bowel habits; persistent sore throat or fever; numbness or tingling in the arms, hands, legs, or feet; severe nausea and vomiting; shortness of breath; swelling in the mouth; swollen stomach; very slow heartbeat; wheezing.
Proper storage of this medicine:
This medicine is usually handled and stored by a health care provider. If you are using this medicine at home, store this medicine as directed by your pharmacist or health care provider. Keep this medicine out of the reach of children and away from pets.
General information: If you have any questions about this medicine, please talk with your doctor, pharmacist, or other health care provider.
This medicine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor. |
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