辛伐他丁和伊曲康唑合用引起的横纹肌溶解导致的急性肾衰

Rhabdomyolysis-induced acute renal failure due to itraconazole and simvastatin association.
Roques S, Lytrivi M, Rusu D, Devriendt J, De Bels D.
SourceIntensive Care Department, Brugmann University Hospital, Brussels, Belgium.

Abstract
Abstract We present the case of an 82-year-old man admitted to our hospital for muscle weakness. He was under simvastatin 20 mg per day and was given pulse itraconazole therapy 8 days before the onset of symptoms for onychomycosis. He developed severe rhabdomyolysis inducing an acute renal failure necessitating renal replacement therapy. He eventually fully recovered. Given the possible concurrent use of simvastatin and itraconazole, awareness of this potential interaction is clinically important.

很大的挑战，好久没读英文了

大家对这个不良反应遇到过吗

知道辛伐他汀有这类不良反应，但还没碰到过。

学习了！学习了！

学习了！学习了！