多药合用者更易跌倒？

新西兰研究人员最近发现：同时使用两种或两种以上处方药的年轻人和中年人，意外跌倒的风险明显增加，跌倒受伤的几率更是比只使用一种或没有使用处方药者高150%。
研究人员还发现：降压药和调血脂药合用者，跌倒的风险比其他人高两倍，而使用平喘药、抗炎药、类固醇和抗抑郁药者，跌倒的风险没有明显增加。
但研究人员称：现在还不清楚，特定药物增加跌倒风险是源自药物本身的作用,还是和要治疗的原发病有关。
跌倒在全世界范围内都是导致损伤和死亡的头号原因，但之前的研究对象多为老年人和儿童。研究人员在较年轻成年人群中的发现和以往在老年人群中的发现类似，这说明：处方药和跌倒风险之间的关系在这个人群中也应该给予关注。



http://consumer.healthday.com/Article.asp?AID=660742


Younger Adults on Multiple Meds at Risk for Falls: Study
Injury risk was doubled compared to those with fewer prescriptions

TUESDAY, Jan. 17 (HealthDay News) -- Young and middle-aged adults who take two or more prescription drugs at any one time may be at increased risk for accidental falls, a new study finds.
The effect is similar to that seen in elderly people, according to the report published online Jan. 17 in the journal Injury Prevention.
In the study, the researchers looked at data from 344 working-age people who died or required hospital admission within 48 hours of an accidental fall at home in Auckland, New Zealand, between 2005 and 2006. They were compared with 352 randomly selected age-matched people in the general population.
The investigators found that people who took two or more prescription drugs were 2.5 times more likely to suffer an injury in an accidental fall than those who took one or no medicine.
The findings held true even after accounting for personal, social and lifestyle factors such as drinking, illicit drug use and amount of sleep, said Dr. Bridget Kool of the University of Auckland and colleagues.
The study also found that taking drugs to lower blood pressure and cholesterol appeared to triple the risk of a fall. Asthma inhalers, anti-inflammatory drugs, steroids and antidepressants did not increase the risk of a fall.
Whether the increased risk of falls associated with certain drugs were a result of the drugs themselves or the underlying conditions they were being used to treat is unclear, the researchers said.
Falls are a leading cause of injury and death worldwide, but most research focuses on older adults and children.
"The findings signal a need for greater awareness of the association between prescription medications and falls in younger adults, whether this is due to the medications, underlying conditions or a combination of both related factors," the study authors concluded in a journal news release.
More information
The American Academy of Orthopaedic Surgeons offers guidelines for preventing falls.
-- Robert Preidt
SOURCE: Injury Prevention, news release, Jan. 16, 2012
Last Updated: Jan. 17, 2012
Copyright © 2012 HealthDay. All rights reserved.

新知识学习了。